Improved molecular detection of dengue virus serotype 1 variants.

نویسندگان

  • Jean-Marc Reynes
  • Sivuth Ong
  • Channa Mey
  • Chantha Ngan
  • Stefan Hoyer
  • Amadou A Sall
چکیده

The dengue virus molecular typing method described by Lanciotti and coworkers (R. S. Lanciotti, C. H. Calisher, D. J. Gubler, G. J. Chang, and A. Vance-Vorndam, J. Clin. Microbiol. 30:545-551, 1992) is used worldwide for diagnosis and surveillance. However, it failed to detect DENV-1 variants in Cambodia due to a point mutation. We describe an improvement of the method that allows the detection of additional DENV-1 strains, including potential variants.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 41 8  شماره 

صفحات  -

تاریخ انتشار 2003